Narcolepsy is a neurological disorder seen as a excessive sleepiness. It’s triggered by destruction of several neurons in a part of our brain called the hypothalamus. The hypothalamus is important in regulating our human hormones, a lot of which control basic functions like sleep and craving for food. Because of the positioning in the brain, reviews have linked narcolepsy to raised weight and type 2 diabetes even.
It’s been theorized that patients with narcolepsy have reduced sensitivity to insulin, much like type 2 diabetics. This study was done to evaluate both blood glucose and extra fat metabolism in a little band of narcoleptics and likened them to a matched up control group that did not have narcolepsy. They used a sophisticated test to measure both blood and fat sugar metabolism, something that had not been done before in old studies of patients with narcolepsy. The results were interesting for the reason that the researchers discovered that narcoleptics acquired increased insulin level of sensitivity in the periphery – the contrary of what they expected.
Liver cell insulin level of sensitivity and pancreatic function were the same as matched controls. Fat metabolism tended to be low in patients with narcolepsy, which may explain in part why narcolepsy is associated with being overweight. The research workers also treated the narcoleptic patients with sodium oxybate, a medicine that improves a few of the narcolepsy symptoms.
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It’s taken during the night, and improves the patients’ sleep quality, although it isn’t a sleep aid. Interestingly, the sodium oxybate increased unwanted fat metabolism, and the narcoleptic patients lost an average of 5.2 kg (11.5 pounds) in the 90 days of the study. The exact mechanism of the weight reduction is as yet not known. The bottom line is that the results of this study do not support an elevated risk of type 2 diabetes in narcoleptics. Also, patients with narcolepsy that are treated with sodium oxybate might lose weight, although the precise system is unclear.
The RM could be used as a measure of what could be raised on any given “off day” due to the fatigue from pieces before the RM. Both the volume foundation and fatigued rep maxes can be improved within a one or multiple cycles and would be looked at as “volume personal records” (volume base) or “rep personal records” (RM), each a distinctive measure of improvement.
While linear three-week blocks with small resets appear to be the most effective and sustainable, other means of sustainability can be accomplished through use of workout-to-workout or week-to-week undulation in work. Continued linear progression beyond three weeks becomes less and less consistent with a more substantial amount of training variables to be controlled for. This is especially true for more complex athletes, myself included.
Progression slows and thus necessitates less of the strength increase week-to-week, more rest, lower quantities, as well as sparing the utilization of AMRAPS, all in an effort to mitigate accumulated training stress. As weeks move and development slows the need for a significant deload becomes more noticeable due to poor lifter performance.
For this reason three week training blocks with smaller intensity and quantity resets are recommended as a way to eliminate dependence on large deloads. The first tier is where our competition actions and foundational lifts reside. Note: They need to still remain chemical substance barbell or dumbbell lifts. It is strongly recommended that when programming use an exercise Max of a recently available or reasonably approximated 2-rep potential (RM) that might be raised any given trip to the start of the program. Referred to as a “Goal Weight” in the initial GZCL Method the concept is to show a known rep utmost (RM) into a higher rep potential with the same weight.